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Devin D. Thorpe

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Monthly Archives: March 2017

New amfAR Grants Enlist Help of Bioengineers to Overcome Obstacles to Curing HIV

Press Release – New York, Feb. 28, 2017 — In a novel approach to conquering HIV, amfAR, The Foundation for AIDS Research, is pairing HIV researchers with bioengineers to address the main barrier to a cure for HIV: the persistent reservoirs of virus not cleared by antiretroviral therapy. A new round of Investment grants, totaling $1.2 million, will support six new research projects aimed at bringing to bear highly advanced technologies that until recently might have belonged in the pages of a science fiction novel.

“Over the past couple of decades, stunning advances in bioengineering have led to the development of new technologies and therapeutics that will likely have a profound impact on treating and eradicating diseases,” said amfAR CEO Kevin Robert Frost. “Many of these exciting new technologies have yet to be evaluated in the realm of HIV cure research, and we hope this new round of grants lays the groundwork for some innovative approaches to a cure.”

The Investment awards are milestone-based grants that provide up to $1.5 million to each research team over four years in three phases. They are part of amfAR’s $100 million Countdown to a Cure for AIDS initiative, which is aimed at developing the scientific basis of a cure by the end of 2020.

Bioengineers with expertise in cutting-edge technologies including microfluidics, gene-editing, nanotechnology, mass spectrometry, and single-cell magnetic levitation will work closely with leading HIV cure scientists to tackle some of the most intractable challenges in HIV cure research.

Magnetic levitation is a technology typically associated with high-speed transportation systems. But Timothy Henrich, M.D., of the University of California, San Francisco, and the amfAR Institute for HIV Cure Research, and bioengineer Utkan Demirci, Ph.D., from the Regents of the University of California, San Francisco, will apply a revolutionary approach called magnetic levitation of single cells to identify and characterize HIV reservoirs. Theorizing that HIV induces a change in the magnetism and density of reservoir cells, the scientists will use a device developed by Dr. Demirci that can suspend a single cell between magnets and measure its density. Such measurements could be used to help distinguish reservoir cells from uninfected cells, and to define a molecular signature that can be targeted by curative interventions.

Mass spectrometry is a method of identifying and quantifying molecules that has become an indispensable tool across a broad range of fields and applications. Harnessing the technology’s ability to “fingerprint” proteins, bioengineer Hui Zhang, Ph.D., and HIV scientist Weiming Yang, Ph.D., both at Johns Hopkins University in Baltimore, will use mass spectrometry to identify molecules on the surface of the cells that differentiate the latent reservoir from uninfected cells. The researchers propose that cell surface markers could aid in the development of vaccines or other interventions to target and eliminate the latent reservoir.

“This is a very exciting round of research grants that forges some unlikely but potentially groundbreaking scientific alliances,” said Rowena Johnston, Ph.D., amfAR vice president and director of research. “These highly innovative projects will undoubtedly move HIV cure research in some extraordinary new directions that, we hope, will get us closer to our goal.”

The following is a full list of Investment grant recipients:

PI: Eli Boritz, MD PhD
Collaborating Bioengineer: David Weitz, PhD
Foundation for the NIH
$200,000
Single-cell transcriptomic analysis of HIV reservoirs before and after systemic interleukin-2 therapy
Distinguishing the reservoir, the collection of HIV-infected cells that persist in the body, from uninfected cells is a central challenge in HIV cure research. Recently, developments in cutting-edge single-cell technologies have vastly increased the number of cells that can be analyzed. One of the pioneers in this field, Dr. David Weitz, is collaborating with Dr. Eli Boritz, an HIV scientist, to use microfluidics to scan millions of human cells for those that constitute the reservoir. Dr. Boritz proposes to use two of the most advanced microfluidic technologies, PACS and inDrop, to isolate and characterize individual reservoir cells from HIV positive people. He aims to identify the molecular signature of the reservoir so that scientists may exploit it for future curative interventions, for example by targeting interventions specifically to reservoir cells, or so that scientists can quantify the reservoir.

PI: Timothy Henrich, MD
Collaborating Bioengineer: Utkan Demirci, PhD
Regents of the University of California, San Francisco, San Francisco CA
$200,000
Single-cell levitation to identify, isolate and characterize HIV reservoirs
Cells carry inherent biological properties that define their magnetism and density. These properties may be altered if the cells encounter certain environmental stressors such as viral infection. Dr. Utkan Demirci developed a revolutionary approach called magnetic levitation of single cells, which harnesses the magnetism of cells to distinguish, for example, cancer cells from non-cancer cells. Now, in collaboration with Dr. Timothy Henrich, a member of the amfAR Institute for HIV Cure Research, Dr. Demirci is using this platform to advance the field of HIV cure research. They propose that reservoir cells can be distinguished from uninfected cells based on the change in magnetism and density induced by the virus itself. Magnetic levitation will be used to isolate the reservoir—thereby distinguishing it from uninfected cells—to define a molecular signature that can be targeted by curative interventions.

PI: Keith Jerome, MD PhD
Collaborating Bioengineer: Kim Woodrow, PhD
University of Washington, Seattle WA
$200,000
Targeted nanocarriers to accelerate depletion of the HIV reservoir
Nanoparticles, highly versatile particles that are a thousand times smaller than a cell, have been shown to be useful in applications ranging from creating synthetic skin for wound healing to cleaning up oil spills. Dr. Kim Woodrow is a bioengineer with expertise in the biomedical use of nanoparticles and has used them as biological timers to deliver pre-programmed doses of drugs. Together with Dr. Keith Jerome, an HIV cure scientist, Dr. Woodrow aims to formulate new drug combinations loaded on to nanoparticles in a two-pronged approach. First, latency-reversing agents are loaded onto the particles to reawaken the latent reservoir and prime the cell for killing by the immune system. Then the particles will carry anti-proliferative drugs that halt processes that feed and maintain the reservoir. The combined approach aims to eradicate the reservoir through direct killing by the immune system and by depriving it of what it needs to renew itself.

PI: Priti Kumar, PhD
Collaborating Bioengineer: Mark Saltzman, PhD
Yale University, New Haven CT
$200,000
Targeted inactivation of integrated HIV through host cell DNA repair pathways
Newly discovered gene-editing systems have energized the field of HIV cure research because of their ability to specifically target and remove HIV from the DNA. However, there are safety issues with most approaches that must be resolved before they can move into the clinic. Dr. Priti Kumar, an HIV cure scientist, proposes a gene-editing approach that solves some of the safety problems. She will use editing tools already present inside the cell and will attempt to disable the provirus by delivering a large DNA sequence that is inserted into the provirus. Her approach to increase delivery efficiency capitalizes on a collaboration with Dr. Mark Saltzman, an expert in the use of nanoparticles for drug delivery. Dr. Saltzman, utilizing FDA approved biopolymers, will engineer nanoparticles containing the ‘editing instructions’ and a homing device that will deliver the loaded particles specifically to the HIV reservoir. Together, they will determine whether this novel gene-editing approach using the cell’s own machinery can eliminate the reservoir and cure HIV.

PI: Jeremy Luban, PhD
Collaborating Bioengineer: Scot Wolfe, PhD
University of Massachusetts Medical Center, Worcester MA
$200,000
Bifunctional nucleases programmed by HIV-1 mRNA for reservoir eradication
Gene-editing systems are a promising approach to HIV cure because they are highly specific to the provirus integrated into the cell’s DNA. However, molecular gene editors often force HIV to mutate its genome to evade being targeted and destroyed. Thus, the next generation of gene-editing approaches involves targeting multiple HIV-specific DNA sequences at once to prevent escape mutations by the virus. Dr. Scot Wolfe, a bioengineer with expertise in a variety of gene-editing systems, has designed a molecular editor, Cpf1, that can deliver up to 10 different instructions to edit HIV into an individual cell. Together with Dr. Jeremy Luban, an HIV scientist, they aim to use this technology to permanently disable the provirus.

PI: Hui Zhang, PhD
Collaborating HIV Scientist: Weiming Yang, PhD
Johns Hopkins University, Baltimore MD
$199,444
Deciphering latency-associated sugar-code to detect and eliminate latent reservoir
Reservoirs of HIV persist even during ART in part because the immune system is not able to distinguish the reservoir from uninfected cells. Identifying and exploiting differences not identified by the immune system would represent a monumental advance in HIV cure research. A powerful technique called mass spectrometry could hold the answer. Like fingerprint technology for proteins, mass spectrometry can identify the collection of molecules present on the cell surface. Dr. Hui Zhang, an expert in mass spectrometry, proposes to use this technology to identify molecules on the surface of the cells that constitute the latent reservoir. Together with Dr. Weiming Yang, an HIV scientist, Dr. Zhang proposes to identify cell surface markers that could aid the development of vaccines or other interventions to target and destroy the latent reservoir.

About amfAR

amfAR, The Foundation for AIDS Research, is one of the world’s leading nonprofit organizations dedicated to the support of AIDS research, HIV prevention, treatment education, and advocacy. Since 1985, amfAR has invested more than $480 million in its programs and has awarded grants to more than 3,300 research teams worldwide.

Outgoing RWJF President and CEO Risa Lavizzo-Mourey Appointed Penn Integrates Knowledge Professor

Press Release – Princeton, N.J. — Risa Lavizzo-Mourey, MD, MBA, who departs the Robert Wood Johnson Foundation this April after nearly 14 years as president and CEO, will join the University of Pennsylvania as the institution’s nineteenth Penn Integrates Knowledge University Professor, effective January 1, 2018. Penn President Amy Gutmann and Provost Vincent Price announced the appointment today.

A world-renowned expert in health policy and geriatric medicine, Lavizzo-Mourey has served the Foundation since 2003 and, for fifteen years before that, as a distinguished professor and administrator at Penn. She will be the Robert Wood Johnson Foundation Population Health and Health Equity Professor with joint faculty appointments in the Department of Medical Ethics and Health Policy in the Perelman School of Medicine, the Department of Health Care Management in the Wharton School, and the Department of Family and Community Health in the School of Nursing.

“I am deeply honored to accept this position and grateful to be given the opportunity to continue vital work in these areas,” said Lavizzo-Mourey. “This professorship will ensure that critical issues surrounding population health and health equity remain the focus of intensive examination, productive collaboration, and far-reaching problem-solving.”

In the announcement, Penn cited Lavizzo-Mourey and the Foundation for its devotion to health including the billion dollar initiative to reverse the nation’s childhood obesity epidemic, the support of programs to help people obtain better health care, the Foundation’s Commission to Build a Healthier America and its landmark 2009 report “Beyond Health Care,” focused on recommendations to improve health at the local, state, and federal levels.

“Whether leading one of the nation’s largest health care philanthropies, advising the White House on health policy, or publishing prolifically in some of the world’s most influential medical journals, Risa Lavizzo-Mourey is an eminent interdisciplinary change-maker,” said President Gutmann. “Her exemplary contributions to geriatrics and other health fields are matched by her devotion to promoting lasting social change and improving the health of all people. We are delighted to welcome home this truly exceptional scholar, clinician, leader, and Penn alumna.”

In her previous tenure at Penn, Lavizzo-Mourey was Sylvan Eisman Professor of Medicine and Director of the Institute on Aging. She began her career at Penn in 1986, after earning an MBA at Wharton in Health Care Administration while completing Penn’s Robert Wood Johnson Foundation Clinical Scholars Program, and during her tenure served as Associate Executive Vice President for Health Policy, Associate Dean for Health Services Research, and Chief of the Division of Geriatric Medicine. At the federal level, she was deputy administrator of what is now the Agency for Health Care Research and Quality; worked on the White House Health Care Reform Task Force, co-chairing the working group on quality of care; has served on numerous federal advisory committees, including the Task Force on Aging Research, the National Committee for Vital and Health Statistics, and the President’s Advisory Commission on Consumer Protection and Quality in the Health Care Industry; and is master and former regent of the American College of Physicians, where she chaired the committees on ethics and human rights. She is a member of the American Philosophical Society.

In addition to an MBA from the Wharton School, Lavizzo-Mourey earned an MD from Harvard Medical School. In recognition of her far-ranging and path-breaking accomplishments, Penn awarded her an honorary Doctor of Laws in 2010.

“Risa Lavizzo-Mourey’s work,” said Provost Price, “embodies Penn’s mission: using innovative, interdisciplinary research to make a tangible impact on improving people’s lives around the world. I am certain that she will continue to be an inspiring catalyst, colleague, mentor, and collaborator across every part of our campus in the years ahead.”

The Penn Integrates Knowledge program was launched by President Gutmann in 2005 as a university-wide initiative to recruit exceptional faculty members whose research and teaching exemplify the integration of knowledge across disciplines and who are appointed in at least two schools at Penn.

Developing World Markets’ Social Impact Note Lends $60.8 Million for Off-Grid Solar and Climate Action

Funds on-lent to 11 microfinance institutions and off-grid solar companies operating in Latin America (Ecuador, Guatemala, Nicaragua), Africa (Kenya, Rwanda, Tanzania), and Asia (India, Kazakhstan, Mongolia)

Press Release – February 28, 2017 — Veteran U.S. social impact investment manager, Developing World Markets (DWM), has invested $60.8 million in 11 businesses promoting renewable energy and climate solutions across Latin America, Africa and Asia. Anchor investors in DWM’s ORCA (Off-Grid, Renewable and Climate Action) Impact Note include two faith-based pension funds, The Church Pension Fund and Wespath Benefits and Investments, with each contributing $30 million. Developing World Markets structured the transactions; the investees include off-grid solar operating companies, D.light, Kingo Energy, and Off-Grid Electric, as well as microfinance institutions Saija Finance, Satin Creditcare Network, KMF (Kazakhstan), XacBank, FDL (Nicaragua), Produbanco (Ecuador), Banco Procredit (Ecuador), and FINCA Nicaragua. Invested funds are earmarked for solar home solutions and other forms of renewable energy, as well as CO2 and greenhouse gas mitigation activities. DWM estimates the funding will enable some 200,000 families to access solar home solutions. Worldwide more than 2.2 billion people live without reliable access to electricity.

“The companies financed by the ORCA Note are employing innovative, market-based mechanisms to solve critical development needs. For the equivalent price of what was previously spent on outdated energy sources such as kerosene, low-income individuals in developing countries can access clean, modern renewable energy technology for their homes and families; addressing not only energy, but health issues as well,” said Peter Johnson, Managing Partner of Developing World Markets. “DWM is honoured to support these pioneering organizations, and we are in turn grateful for the support of our investors.”

The ORCA Impact Note is U.S. dollar denominated with a coupon of 5.85%. Its four year term will run through December 27, 2020. The structuring of the Note was unique in its transparency, as borrowers were pre-identified and noteholders were certain of where and how the proceeds would be used, prior to investment. Since its founding in 1994, DWM has structured and invested over $1 billion into more than 170 companies across more than 50 developing countries.

“The Church Pension Fund was pleased to serve as an anchor investor, which helped bring other investors to the table to provide renewable energy finance loans to social businesses in the developing world. This investment will impact the lives of people on three different continents and is reflective of our commitment to earning a competitive rate of return. We look forward to building our relationship with Developing World Markets as we continue to explore future SRI opportunities,” said Roger Sayler, Managing Director and Chief Investment Officer of The Church Pension Fund.

“Wespath was pleased to commit to the DWM ORCA Impact Note, an investment that focuses on providing critical energy access in the developing world,” said Dave Zellner, Chief Investment Officer of Wespath Benefits and Investments. “This impact investment, which continues a more than decade-long relationship with DWM, reflects the intent that our global investment activities have a positive impact on society and the environment while earning a market rate of return.”

Additional investors in the Note include King & Shaxson (London), Invethos (Switzerland) and Developing World Markets (United States). Law firms McGuire Woods, LLP in the United States and Arendt & Medernach in Luxembourg advised on the transaction.

About Developing World Markets

Developing World Markets (DWM) is an emerging and frontier markets focused, impact investment firm. DWM seeks investments that provide risk-appropriate returns and measurable social or environmental benefits. Since its founding in 1994, DWM has structured and invested over $1 billion into more than 170 companies across more than 50 developing countries. The firm is headquartered in Stamford, CT, USA. For more information visit: www.dwmarkets.com.

About Wespath Benefits and Investments

Wespath Benefits and Investments (Wespath) is a general agency of The United Methodist Church with fiduciary responsibility for the benefit plans it administers and the assets it invests.

Wespath supports benefit plans for more than 100,000 participants around the world, and investments for more than 100 United Methodist-affiliated endowments, foundations and other institutions. Wespath manages approximately $21 billion in assets, proactively incorporating environmental, social and governance factors. Our activities reflect the stated values of the Church and help strengthen financial sustainability across all investments, consistent with our fiduciary obligation to all.

Wespath is the largest reporting faith-based pension fund in the world, and among the top 100 pension funds in the United States. As a sustainable investor, Wespath is committed to active ownership through corporate and public policy engagement, proxy voting and the management of excessive sustainability risk. Wespath’s sustainable investment activities are carried out by Wespath Investment Management, the agency’s investments division. Learn more at www.wespath.org.

About The Church Pension Fund

The Church Pension Fund (CPF) is an independent financial services organization that serves the Episcopal Church. With approximately $12 billion in assets, CPF and its affiliated companies, collectively the Church Pension Group (CPG), provide retirement, health, and life insurance benefits to clergy and lay employees of the Episcopal Church. CPG also offers property and casualty insurance as well as book and music publishing, including the official worship materials of the Episcopal Church. Learn more at www.cpg.org.

Hartford Funds Launches Hartford Global Impact Fund, Expanding Socially Responsible Investing Lineup

Press Release – March 01, 2017 09:00 AM Eastern Standard Time – RADNOR, Pa. — Hartford Funds today announced that it has launched the Hartford Global Impact Fund (A-share: HGXAX). Sub-advised by Wellington Management, the Hartford Global Impact Fund will seek long-term capital appreciation by investing in companies that focus their operations in areas that the Fund believes are likely to address the world’s major social and environmental challenges.

The Fund invests in companies that the sub-adviser believes are likely to address major social and environmental challenges including, but not limited to, health, clean water and sanitation, financial inclusion, alternative energy, and resource efficiency, as determined by Wellington.

“We’re delighted to expand our socially responsible investment solutions for investors who want to align their portfolios with their values,” said Anita Baldwin, Managing Director and Head of Research for Hartford Funds.

The Hartford Global Impact Fund complements Hartford Funds’ existing socially responsible investing solution, the Hartford Environmental Opportunities Fund (HEOMX). Launched in February 2016, the Environmental Opportunities Fund seeks long-term capital appreciation by identifying companies it believes represent attractive investments and also address environmental challenges and/or seeks to improve the efficiency of resource consumption.

“The design and launch of the Hartford Global Impact Fund aligns with our human-centric investing philosophy and is a direct response to increasing advisor and investor demand for more products that take ESG factors into consideration,” Baldwin added.

Wellington Management’s Eric Rice, PhD., Managing Director and Portfolio Manager, and Patrick Kent, CFA, CMT, Managing Director and Portfolio Manager, will manage the Hartford Global Impact Fund.

About Hartford Funds

Founded in 1996, Hartford Funds is a leading provider of mutual funds and 529 college savings plans. Using its human-centric investing approach, Hartford Funds creates strategies and tools designed to address the needs and wants of investors. Leveraging partnerships with leading practice management experts, Hartford Funds delivers insight into the latest demographic trends and investor behavior.

As of October 24, 2016, the firm’s line-up includes more than 55 mutual funds in a variety of styles and asset classes, and five strategic beta ETFs. Its mutual funds (with the exception of certain fund of funds) are sub-advised by Wellington Management or Schroder Investment Management North America Inc. The strategic beta ETFs offered by Hartford Funds are designed to help address investors’ evolving needs by leveraging a unique risk-optimized approach, which identifies risks within each asset class and then deliberately and systematically re-allocates capital toward risks more likely to enhance return potential. Hartford Funds has mutual fund assets under management of $81.5 billion as of December 31, 2016 (excluding assets used in certain annuity products). For more information about our investment family, visit www.hartfordfunds.com.

Important Information

All investments are subject to risk, including the possible loss of principal. There is no guarantee the Fund will achieve its stated objective. The Fund’s share price may fluctuate due to market risk and/or security selections that may underperform the market or relevant benchmarks. Foreign investments can be riskier and more volatile than U.S. investments due to the adverse effects of currency exchange rates, differences in market structure and liquidity, as well as political and economic developments in foreign countries and regions (e.g., “Brexit”). These risks are generally greater for investments in emerging markets. Small-cap securities can have greater risk and volatility than large-cap securities. Investing in companies that seek to address major social and environmental challenges may cause the Fund to forego certain investment opportunities and underperform Funds that do not have a similar focus. By investing in cash and money market investments, the Fund may lose the benefit of market upswings. Because it invests in a master portfolio, the Fund is also subject to the risks related to a master-feeder structure.

Hartford Funds refers to Hartford Funds Management Group, Inc., and its subsidiaries, including the mutual funds’ investment manager, Hartford Funds Management Company, LLC (HFMC), the mutual funds’ distributor, Hartford Funds Distributors, LLC, Member FINRA, as well as Lattice Strategies LLC, a wholly owned subsidiary of HFMC, which serves as the adviser to exchange-traded funds (ETFs). Certain funds are sub-advised by Wellington Management Company LLP or Schroder Investment Management North America Inc. Schroder Investment Management North America Ltd. serves as a secondary sub-adviser to certain funds. ETFs are distributed by ALPS Distributors, Inc. (ALPS). Hartford Funds is not affiliated with any fund sub-adviser or ALPS. The MIT AgeLab is not an affiliate or subsidiary of Hartford Funds.

Investors should carefully consider the investment objectives, risks, charges, and expenses of a fund before investing. This and other information can be found in the fund’s prospectus, which should be read carefully before investing. To obtain a mutual fund prospectus or summary prospectus, please call 888-843-7824 (retail) or 800-279-1541 (institutional); ETF prospectuses can be obtained by calling 415-315-6600.

“The Hartford” is The Hartford Financial Services Group Inc. (“HFSG”) and its subsidiaries. HFD is a subsidiary of The HFSG.

HIG-W

Some of the statements in this release may be considered forward-looking statements as defined in the Private Securities Litigation Reform Act of 1995. We caution investors that these forward-looking statements are not guarantees of future performance, and actual results may differ materially. Investors should consider the important risks and uncertainties that may cause actual results to differ. These important risks and uncertainties include those discussed in The Hartford’s Quarterly Reports on Form 10-Q, our 2015 Annual Report on Form 10-K and the other filings The Hartford makes with the Securities and Exchange Commission. We assume no obligation to update this release, which speaks as of the date issued.

From time to time, The Hartford may use its website to disseminate material company information. Financial and other important information regarding The Hartford is routinely accessible through and posted on our website at http://ir.thehartford.com. In addition, you may automatically receive email alerts and other information about The Hartford when you enroll your email address by visiting the “Email Alerts” section at http://ir.thehartford.com.

“Don’t Cramp My Style” with goPuff and Camions of Care to Bring Tampons to Women in Need

On-Demand Delivery Service to Donate One Tampon for Every Order in Portland and Seattle During Women’s History Month

Press Release – PHILADELPHIA, PA (March 1, 2017)goPuff, the on-demand convenience store delivery service, today announced a partnership with Camions of Care, a youth-run nonprofit 501c3 organization that strives to manage menstrual hygiene through advocacy, education, and service, to launch the “Don’t Cramp My Style” tampon donation and feminine health awareness campaign for Women’s History Month in March.

As part of the collaboration, goPuff will donate one tampon for every order placed in Portland, OR and Seattle, WA, starting on March 1st through 31st. At the end of the campaign, Camions of Care will distribute the tampons to homeless women in need in both cities through scheduled events and weekly distribution initiatives.

“As a company founded on the premise of providing a convenient way for students, young professionals and families to access the essential items they need, the issue of women’s accessibility to personal hygiene products is one we are passionate about,” said Taylor Goldman, Director of Content for goPuff. “We believe that easy, affordable access to these products for women everywhere–despite their age, profession or socioeconomic status– is crucial. We’re excited to bring awareness to this issue and elevate the conversation about accessibility for women in need through our partnership with Camions of Care.”

“As we continue our mission to push systemic social change around menstrual equity, it’s partners like goPuff who are helping make that vision a reality, one tampon at a time,” said Nadya Okamoto, Founder and Executive Director of Camions of Care.

No extra steps are needed; consumers in Portland and Seattle are auto-enrolled in the donation campaign at no inconvenience. To participate in one of these cities, simply place an order – choosing from more than 3,000 products across 20-plus categories on goPuff’s website or mobile app – which is delivered in 30 minutes or less. Among the items goPuff delivers are women’s products, including tampons, sanitary pads, condoms and Plan B contraceptives.

goPuff currently serves fifteen major U.S. markets and operates from 12pm-4:30am in most cities and open 24/7 in Philadelphia, PA, Chicago, IL, Phoenix, AZ, Tucson, AZ and Washington DC. The service charges a flat $1.95 delivery charge, which is waived for orders over $49.

goPuff is available on iOS and Android. For more information on goPuff, visit http://gopuff.com.

About goPuff

goPuff is an on-demand delivery service that is replacing the need for convenience stores. The company warehouses and delivers thousands of products in 30 minutes or less to your door, for a flat $1.95 delivery charge. As the fastest and most affordable on-demand delivery option available in the marketplace, goPuff takes convenience seriously, bringing you what you need, when you need it, operating from 12 PM to 4:30am in most cities and 24/7 in Philadelphia, Chicago, Phoenix and Washington DC. goPuff currently operates in fifteen major markets (Austin, TX; Boston, MA; Chicago, IL; Columbus, OH; Denver, CO; Manayunk, PA; New York, NY; Philadelphia, PA; Phoenix, AZ; Portland, OR; Seattle, WA; State College, PA; Pittsburgh, PA; Tucson, AZ; Washington, DC) and continues to expand rapidly. For more information on goPuff, visit http://gopuff.com/.

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